Journal
JOURNAL OF NEURO-ONCOLOGY
Volume 82, Issue 1, Pages 81-83Publisher
SPRINGER
DOI: 10.1007/s11060-006-9241-y
Keywords
glioblastoma; temodar; radiotherpy
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Concurrent temozolomide (TMZ) and radiotherapy is the new standard of care for patients with newly diagnosed glioblastoma. In 51 consecutive patients treated according to this regimen, 7 patients (14%) manifested surgically confirmed early necrosis without evidence of recurrent tumor. This observation suggests that daily TMZ may represent a potent radiosensitizing regimen.
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