3.9 Article

Galactosaminoglycan function and oligosaccharide structure determination

Journal

THESCIENTIFICWORLDJOURNAL
Volume 7, Issue -, Pages 233-241

Publisher

HINDAWI LTD
DOI: 10.1100/tsw.2007.63

Keywords

dermatan sulfate; oligosaccharide structural analysis; electrospray mass spectrometry; MS/MS sequencing

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This review will discuss the importance of sequencing long chondroitin sulfate and dermatan sulfate chains specifically derived from decorin. Decorin is a member of the small leucine-rich repeat proteoglycans and ubiquitously expressed primarily in the skin. Sequence information and diverse function of glycosaminoglycans is further influenced by variable expression through the core protein indicating the importance to analyse glycosaminoglycans from specific proteoglycans.

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