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miRNAs in the biology of cancers and viral infections

Journal

CURRENT MEDICINAL CHEMISTRY
Volume 14, Issue 2, Pages 191-197

Publisher

BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/092986707779313417

Keywords

non-coding small RNA; microrna; carcinogenesis; tumorigenesis; viral pathogenesis

Funding

  1. Intramural NIH HHS Funding Source: Medline
  2. NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES [ZIAAI001023, ZIAAI000547, Z01AI000547, Z01AI001023] Funding Source: NIH RePORTER

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MicroRNAs (miRNAs) are non-coding small RNAs that play important roles in a variety of biological pathways including cellular proliferation and apoptosis. Recent studies have linked the expression of selected miRNAs to carcinogenesis and viral pathogenesis. Here, we will discuss examples of roles served by cellular miRNAs and virus-encoded miRNAs in the development of cancers and viral diseases.

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