Journal
PSYCHIATRY AND CLINICAL NEUROSCIENCES
Volume 61, Issue 3, Pages 323-325Publisher
BLACKWELL PUBLISHING
DOI: 10.1111/j.1440-1819.2007.01649.x
Keywords
alternative treatment; kamishoyosan; kampo; premenstrual dysphoric disorder
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The purpose of the present paper was to investigate the efficacy of kamishoyosan (TJ-24), a traditional Japanese herbal formula (kampo), for outpatients with premenstrual dysphoric disorder (PMDD) as an alternative treatment. Thirty patients with PMDD were treated with TJ-24 for six menstrual cycles. Nineteen patients (63.3%) had > 50% improvement in the total score of the Hamilton Depression Rating Scale (HAM-D) Scale (17 items) in the late luteal phase. Fourteen patients (46.7%) went into remission (total HAM-D score < 7). In the present study many patients with PMDD were successfully treated with TJ-24.
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