Journal
JOURNAL OF ORTHOPAEDIC RESEARCH
Volume 25, Issue 1, Pages 11-22Publisher
WILEY
DOI: 10.1002/jor.20305
Keywords
biomaterials; orthopedic; tissue engineering; nanocomposites; nanofibers
Categories
Funding
- NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES [Z01AR041113, R01AR048756, Z01AR041178, R01AR042639] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE OF DENTAL &CRANIOFACIAL RESEARCH [T32DE015355, R01DE015164] Funding Source: NIH RePORTER
- Intramural NIH HHS Funding Source: Medline
- NIAMS NIH HHS [R01 AR42639, R01 AR48756, Z01 AR41113] Funding Source: Medline
- NIDCR NIH HHS [1 T32 DE 015355-01, R01 DE15164] Funding Source: Medline
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Advancements in nanobiotechnology are revolutionizing our capability to understand biological intricacies and resolve biological and medical problems by developing subtle biomimetic techniques. Nanocomposites and nanostructured materials are believed to play a pivotal role in orthopedic research since bone itself is a typical example of a nanocomposite. This article reviews current strategies using nanobiomaterials to improve current orthopedic materials and examines their applications in bone tissue engineering. Preliminary investigations support the potential of nanobiomaterials in orthopedic applications; however, significant advancements are necessary to achieve clinical use. Overall, current trends in nanobiotechnology foreshadow a bright future through the use of nanobiomaterials in the orthopedic domain. (c) 2006 Orthopaedic Research Society. Published by Wiley Periodicals, Inc.
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