Journal
NATURE REVIEWS GENETICS
Volume 8, Issue 1, Pages 58-69Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nrg2025
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Funding
- NHLBI NIH HHS [U01 HL066611] Funding Source: Medline
- NATIONAL HEART, LUNG, AND BLOOD INSTITUTE [U01HL066611] Funding Source: NIH RePORTER
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The mouse has been a powerful force in elucidating the genetic basis of human physiology and pathophysiology. From its beginnings as the model organism for cancer research and transplantation biology to the present, when dissection of the genetic basis of complex disease is at the forefront of genomics research, an enormous and remarkable mouse resource infrastructure has accumulated. This review summarizes those resources and provides practical guidelines for their use, particularly in the analysis of quantitative traits.
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