Journal
NATURAL PRODUCT RESEARCH
Volume 21, Issue 7, Pages 641-645Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/14786410701371165
Keywords
Spiranthes australis (R. Brown) Lindl; dihydroflavanoids; anticancer activity
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A new dihydroflavanoid was obtained from the root of Spiranthes australis (R. Brown) Lindl, a traditional Chinese medicinal herb. The structure was elucidated as (2S)-5,2',6'-trihydroxy-6-lavandulyl-4-(gamma,gamma-dimethylallyl)-2,2-dimethylpyrano-[5,6 : 7,8]-flavanone by spectroscopic methods including UV, IR, HR-EI-MS, ESI-MS, 1D NMR and 2D NMR techniques, and subsequently, the anticancer activities of the compound to inhibit human cancer cells' growth including A549, BEL-7402, SGC-7901, MCF-7, HT-29, K562, and A498 cell lines by MTT method was evaluated in vitro.
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