Journal
NATURAL PRODUCT RESEARCH
Volume 21, Issue 4, Pages 303-309Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/14786410701192702
Keywords
Leguminosae; Gleditsia sinensis Lam.; spine; ellagic acid glycoside; antifungal activity
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Two ellagic acid glycosides were isolated by bioassay-guided fractionation from the antimicrobial ethyl acetate fraction of the ethanol extract from Gleditsia sinensis spines, and identified as 3-O-methylellagic acid-4'-(5 '' acetyl)-alpha-L-arabinofuranoside (1) and 3-O-methylellagic acid-4'-O-alpha-L-rhamnopyranoside (2). Both compounds were isolated from this plant species for the first time, and 1 is a new compound. The two compounds showed significant antifungal activity against the spore germination of rice blast fungus Magnaporthe grisea, with an IC50 value of 13.56 mu g mL(-1) for 1 and 16.14 mu g mL(-1) for 2.
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