Journal
ACCOUNTS OF CHEMICAL RESEARCH
Volume 40, Issue 4, Pages 258-266Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ar6000523
Keywords
-
Categories
Ask authors/readers for more resources
Phytochromes are sensory photoreceptors that, upon light irradiation, can be transformed between an inactive and an active state. The conversion is initiated by the photoisomerization of the cofactor, a linear methine-bridged tetrapyrrole, followed by conformational relaxations of the chromophore and the protein matrix that finally leads to the formation of the signaling state. To elucidate the underlying molecular processes, resonance Raman spectroscopy combined with quantum chemical calculations constitutes a powerful approach since it allows determination of the chromophore structure in the various states of phytochrome. On the basis of these studies, a molecular model for the photoinduced reaction cycle is derived. Phytochromes are sensory photoreceptors that, upon light irradiation, can be transformed between an inactive and an active state. The conversion is initiated by the photoisomerization of the cofactor, a linear methine-bridged tetrapyrrole, followed by conformational relaxations of the chromophore and the protein matrix that finally leads to the formation of the signaling state. To elucidate the underlying molecular processes, resonance Raman spectroscopy combined with quantum chemical calculations constitutes a powerful approach since it allows determination of the chromophore structure in the various states of phytochrome. On the basis of these studies, a molecular model for the photoinduced reaction cycle is derived.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available