Journal
EXPERT OPINION ON BIOLOGICAL THERAPY
Volume 7, Issue 1, Pages 1-3Publisher
INFORMA HEALTHCARE
DOI: 10.1517/14712598.7.1.1
Keywords
cornea; gene therapy; imaging; limbal epithelial stem cells; regulations; stem cell therapy
Funding
- Medical Research Council [G84/6715] Funding Source: Medline
- MRC [G84/6715] Funding Source: UKRI
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Restoring vision in patients suffering from previously intractable blinding ocular surface disease has become possible with the advent of techniques for ex vivo expansion and transplantation of limbal epithelial stem cells onto the cornea. This approach represents one of the few adult stem cell therapies presently in the clinic. This article highlights several key research areas where progress will be made to specifically understand the biology and therapeutic potential of limbal epithelial stem cells, which may have an applicability to the understanding of other adult stem cell populations.
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