Journal
CHEMICAL SOCIETY REVIEWS
Volume 36, Issue 3, Pages 458-470Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/b615227a
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Funding
- NIAID NIH HHS [AI062014] Funding Source: Medline
- NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES [F32AI062014] Funding Source: NIH RePORTER
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There is a growing need for technological advancements to combat agents of chemical and biological warfare, particularly in the context of the deliberate use of a chemical and/or biological warfare agent by a terrorist organization. In this tutorial review, we describe methods that have been developed both for the specific detection of biological and chemical warfare agents in a field setting, as well as potential therapeutic approaches for treating exposure to these toxic species. In particular, nerve agents are described as a typical chemical warfare agent, and the two potent biothreat agents, anthrax and botulinum neurotoxin, are used as illustrative examples of potent weapons for which countermeasures are urgently needed.
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