Journal
MICROBIOLOGY AND IMMUNOLOGY
Volume 51, Issue 1, Pages 105-110Publisher
CENTER ACADEMIC PUBL JAPAN
DOI: 10.1111/j.1348-0421.2007.tb03880.x
Keywords
hsp65; Mycobacterium tuberculosis; M. avium complex; identification; AvaII PRA
Categories
Ask authors/readers for more resources
To evaluate the usefulness of the AvaII PRA method targeting 644-bp hsp65 gene for the direct detection of pathogenic mycobacteria from clinical specimens, we applied this method to 40 sputum samples and compared the results to those obtained by IS6110 PCR. Although this method showed a sensitivity slightly lower than IS6110 PCR (97.5% vs. 100%), it detected infections of M. avium complex (MAC) in two patients, which was not possible by IS6110 PCR. We conclude that Avall PRA is a highly effective method for directly detecting pathogenic mycobacteria in primary clinical specimens.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available