Journal
LETTERS IN ORGANIC CHEMISTRY
Volume 4, Issue 1, Pages 54-59Publisher
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/157017807780037414
Keywords
aza-Michael addition; amines; synthetic methods; electron-deficient alkenes; HClO4-SiO2; solvent-free
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An efficient aza-Michael addition of amines to a series of alpha,beta-unsaturated ketones, carboxylic esters, nitriles and chalcones has been carried out using perchloric acid supported over silica gel (HClO4-SiO2) at room temperature in high yields under solvent-free reaction conditions.
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