Journal
ARTIFICIAL ORGANS
Volume 31, Issue 4, Pages 268-273Publisher
WILEY
DOI: 10.1111/j.1525-1594.2007.00374.x
Keywords
alveolar ridge augmentation; blood platelets; bone marrow cells; dental implantation; stem cell
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In order to increase the amount of available bone where dental implants must be placed, the present study has associated platelet-rich plasma (PRP) and mononuclear cells (MNCs) from bone marrow aspirate and bone scaffold (BS) in 32 patients aged between 45 and 75 years old. The MNC attainment and the adherence to the BS were confirmed through histology, cell culture, and scanning electron microscopy. The clinical results, analyzed by computed tomography, have showed that the scaffolds were well integrated and adapted to the cortical bone. We can conclude that the process of healing observed in the patients was due to the presence of mesenchymal stem cell in MNC fraction in the bone grafts.
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