Journal
CANCER LETTERS
Volume 336, Issue 1, Pages 8-17Publisher
ELSEVIER IRELAND LTD
DOI: 10.1016/j.canlet.2013.04.032
Keywords
Cancer; Superparamagnetic nanoparticles; Targeting; Imaging; Anticancer drugs
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Funding
- Slovene Human Resources Development and Scholarship Fund [11011-39/2011-4]
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Iron-oxide nanoparticles of small dimensions that have superparamagnetic properties show immense potential to revolutionize the future of cancer theranostics, the combinatorial diagnosis and therapeutic approach towards cancer. Superparamagnetic iron-oxide nanoparticles (SPIONs) have unique magnetic properties, due to which they show excellent tumor-targeting efficiency, and this paves the way for effective personalized cancer treatment. The aim of this review is to focus on the ability of SPIONs to perform multiple roles in the field of cancer biology, such as in diagnosis, monitoring, targeting and therapy. Also, other topics are discussed, including the synthesis of SPIONs, the challenges and recent advances. (C) 2013 Elsevier Ireland Ltd. All rights reserved.
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