Journal
IUBMB LIFE
Volume 59, Issue 8-9, Pages 506-512Publisher
WILEY
DOI: 10.1080/15216540701194113
Keywords
protein motions; conformation space; energy landscape
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Protein motions are complex and a good way to describe them is in terms of a very high- dimensional conformation space. We give here a simple explanation of the conformation space and the energy landscape, the conformational motions and protein reactions, based on an analogy to a traffic problem. The analogy provides insight into the slaving of protein processes to bulk solvent. fluctuations, in both the native and unfolded states.
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