Journal
INTERNATIONAL JOURNAL OF OBSTETRIC ANESTHESIA
Volume 16, Issue 1, Pages 40-49Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.ijoa.2006.07.005
Keywords
postpartum haemorrhage; recombinant activated factor VII
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Massive obstetric haemorrhage is a life-threatening emergency that remains a major cause of maternal mortality. Conventional management is aimed at optimising uterine tone, replacing circulating volume and blood products, and surgery to achieve haemostasis. Recently there have been numerous reports of the (unlicensed) use of recombinant activated factor VII in the management of major obstetric haemorrhage. We report our experience of using it in the treatment of major post-partum haemorrhage in four previously healthy parturients. The published reports of recombinant activated factor VII use in post-partum haemorrhage (unrelated to pre-existing coagulopathies) are compared. (c) 2006 Elsevier Ltd. All rights reserved.
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