Journal
CANCER LETTERS
Volume 337, Issue 1, Pages 22-25Publisher
ELSEVIER IRELAND LTD
DOI: 10.1016/j.canlet.2013.05.034
Keywords
Cancer; 3 ' Untranslated regions; Competing endogenous RNA; MicroRNA; Posttranscriptional regulation
Categories
Funding
- Natural Science Foundation of China [81172456]
- Natural Science Foundation of Shanghai [124119a5502]
- Ministry of Education of the People's Republic of China [JFF157001]
Ask authors/readers for more resources
Accumulating evidence suggests that 3' untranlated regions (3' UTRs) are critical for spatial and temporal gene expression in both physiological and pathological conditions. The reprogramming of 3' UTRs by various means is a common phenomenon in cancer; disturbances of 3' UTRs significantly increase the risk of cancer susceptibility by acting both in cis and in trans. In this manuscript, we provide an update and perspective on recent advances made in understanding the emerging roles for 3' UTRs in cancer development and hint at the potential future applications of 3' UTRs in cancer diagnosis and therapy. (C) 2013 Elsevier Ireland Ltd. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
