Journal
MINI-REVIEWS IN MEDICINAL CHEMISTRY
Volume 7, Issue 2, Pages 171-180Publisher
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/138955707779802552
Keywords
Antioxidant; calorie restriction; estrogen; free radical; glutathione; oxidation; oxidative stress; sirtuin; therapy; vitamin C; vitamin E
Categories
Ask authors/readers for more resources
There is considerable evidence showing that oxidative damage is one of the earliest neuronal and pathological changes of Alzheimer disease and many, if not all, of the etiological and pathological causes of the disease are related, directly or indirectly, to free radical production and oxidative damage. Here we summarize the current body of knowledge suggestive that oxidative damage is, if not the key factor, certainly a major factor in Alzheimer disease. As such, therapeutic modalities encompassing antioxidants may be an effective approach to the treatment of neurodegenerative diseases and delay the aging process.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available