Journal
CANCER LETTERS
Volume 289, Issue 2, Pages 140-150Publisher
ELSEVIER IRELAND LTD
DOI: 10.1016/j.canlet.2009.07.004
Keywords
KSHV; Oncogenesis; AIDS-related malignancies; Viral latency; Lytic replication
Categories
Funding
- NIAID [T32-AI007001]
- MSTP [T32-GM008719]
- NIH [CA096500, DE18281, HL083469]
Ask authors/readers for more resources
Kaposi sarcoma-associated herpesvirus (KSHV) is a double-stranded DNA herpesvirus belonging to the gamma-herpesvirinae subfamily. KSHV has been associated with the development of three neoplastic diseases: Kaposi sarcoma (KS), primary effusion lymphoma (PEL), and multicentric Castleman disease (MCD). In this review, we discuss the three KSHV-associated malignancies, KSHV genome, latent and lytic aspects of the viral lifecycle, putative viral oncogenes, as well as therapeutic regimens used for the treatment of KS, PEL, and MCD. (C) 2009 Elsevier Ireland Ltd. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
