Synthesis of Stannic(IV) complexes: Their structural elucidation in solid and solution state and antimicrobial activity

A series of organotin(IV) thiocarboxylates have been synthesized with the general formula R2SnL2 and R3SnL (R = Ph-2(I), Me-3(II), n-Bu-3(III), Ph-3(IV), Cy-3(V), Me-2(VI), n-Bu-2(VII), and L = piperidine-1-thiocarboxylic acid) in anhydrous toluene under the reflux conditions. The complexes were characterized by microanalysis, IR, H-1 and C-13 NMR, mass spectrometry, and XRD. NMR data revealed that thiocarboxylic acid acts as bidentate, and complexes exhibit the four-coordinated geometry in solution state. In solid state, diorganotin complexes exhibit the hexa-coordinated geometry whereas the triorganotin(IV) compounds show the five-coordinated geometry. These complexes were also tested for their antimicrobial activity along with the ligand against different animals, plant pathogens, and Artemia salina. All complexes with few exceptions show high activity as compared to the ligand. (c) 2007 Wiley Periodicals, Inc.