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2-C-methylerythritol phosphate pathway of isoprenoid biosynthesis as a target in identifying new antibiotics, herbicides, and immunomodulators: A review

Journal

APPLIED BIOCHEMISTRY AND MICROBIOLOGY
Volume 43, Issue 2, Pages 115-138

Publisher

PLEIADES PUBLISHING INC
DOI: 10.1134/S0003683807020019

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Specific inhibitors of 2-C-methylerythritol phosphate pathway (MEP-pathway), including compounds obtained based on its metabolites, may compose a new class of antibiotics combining high efficiency and low toxicity. MEP-pathway of isoprenoid biosynthesis is a promising target in identifying new herbicides, immunomodulators, and other physiologically active compounds.

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