Journal
CANCER JOURNAL
Volume 16, Issue 4, Pages 348-353Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/PPO.0b013e3181eb3358
Keywords
myeloid-derived suppressor cells; tumor immunology; cancer vaccines
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Myeloid-derived suppressor cells are one of the major factors responsible for immune suppression in cancer. They also contribute to limited efficacy of current vaccination strategies. Here, we give an overview of the myeloid-derived suppressor cells field focusing primarily on the studies in cancer patients and current and future therapeutic options targeting these cells.
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