Journal
CANCER INVESTIGATION
Volume 27, Issue 8, Pages 844-850Publisher
TAYLOR & FRANCIS INC
DOI: 10.1080/07357900902744502
Keywords
CD133; CD44; CD166; Expression; Colon; Colorectal; Cancer; Survival
Categories
Funding
- Friedrich-Baur-Stiftung, Germany [0015/2007]
- Wilhelm Sander-Stiftung, Germany [2004.111]
Ask authors/readers for more resources
CD133, CD44, and CD166 are cell surface markers that have recently been associated with colorectal cancer stem cells. As which of these markers has the greatest impact on patient prognosis is currently unknown, we compared their expression and prognostic significance in 110 colorectal adenocarcinomas. We demonstrate that expression of CD133 correlates with that of CD166, while both do not correlate with CD44. We show that CD133 is the best sole marker to predict low patient survival, while the combined analysis of all three markers may be superior in identification of low-, intermediate-, and high-risk cases of colorectal cancer.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available