Journal
CHRONOBIOLOGY INTERNATIONAL
Volume 24, Issue 3, Pages 463-470Publisher
TAYLOR & FRANCIS INC
DOI: 10.1080/07420520701420675
Keywords
alcohol; melatonin suppression; dim light
Categories
Funding
- NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM [R01AA013252] Funding Source: NIH RePORTER
- NIAAA NIH HHS [AA13252] Funding Source: Medline
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The study objective was to determine the acute effects of a moderate evening close of alcohol on salivary melatonin levels in humans with stable prior sleep-wake histories and in a controlled environment. Twenty-nine adults (nine males) ages 21 to 25 (M = 22.6, SD = 1.2) yrs adhered to a 10-day at-home stabilized sleep Schedule followed by three in-lab adaptation, placebo, and alcohol (order counterbalanced) study nights. Alcohol (vodka: 0.54 g/kg for men and 0.49 g/kg for women) or placebo beverage was consumed over 30 min, ending I It before stabilized bedtime. At 140 and 190 min after alcohol administration, melatonin level was reduced by 15% and 19%, respectively, in comparison to placebo. The findings indicate that a moderate dose of alcohol in the evening suppressed melatonin in young adults.
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