Journal
NEUROLOGIST
Volume 13, Issue 2, Pages 57-72Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/01.nrl.0000254705.39956.34
Keywords
multiple sclerosis; differential diagnosis; optic neuritis; Lyme disease; lupus; vitamin B12 deficiency; psychiatric disease
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Objective: This article will discuss the diagnosis of multiple sclerosis (MS), with particular attention to differentiating it from other diseases that can mimic it. Methods: We reviewed our own data, as well as the published experience on the differential diagnosis of MS and the most common errors leading to misdiagnosis. Results: Psychiatric diseases are mistaken for multiple sclerosis more often than any other conditions. Other multifocal illnesses or white-matter diseases are seldom confused with multiple sclerosis. Conclusion: Neurologists are most likely to misdiagnose multiple sclerosis in patients who have psychiatric problems or who have uncommon presentations of common diseases such as migraine, stroke, or neuropathies.
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