Journal
TRENDS IN CELL BIOLOGY
Volume 17, Issue 1, Pages 19-25Publisher
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tcb.2006.11.005
Keywords
-
Categories
Ask authors/readers for more resources
Over the past few years, scientists have realized that many cellular and developmental processes, including pancreatic beta-cell growth and differentiation, stem cell and progenitor cell proliferation and cancer cell metastasis, occur in what are known as 'vascular niches'. Despite increasing numbers of reports on these niches, few common mechanisms have been identified to explain their various effects. Here, we define the term 'vascular niche' and suggest that a common and conserved feature of this niche is to provide a basement membrane to cells that are unable to form their own. We further propose that these cells require a vascular niche when they retain a high degree of plasticity.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available