Journal
PSYCHIATRIC CLINICS OF NORTH AMERICA
Volume 30, Issue 3, Pages 511-+Publisher
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.psc.2007.04.001
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This article opens with a brief history of pharmacologic treatment of schizophrenia. It then discusses the definition and treatment of treatment-resistant schizophrenia, with particular attention to clinical, biological and neuroimaging correlates, as well as the best treatment options, including the use of clozapine in patients who meet the definition of treatment-resistant schizophrenia.
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