Journal
MICROVASCULAR RESEARCH
Volume 74, Issue 2-3, Pages 159-171Publisher
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.mvr.2007.08.005
Keywords
angiogenesis; gene therapy; stem cells; endothelial progenitor cell
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Funding
- NATIONAL HEART, LUNG, AND BLOOD INSTITUTE [R01HL063414, R01HL057516, R01HL080137, R01HL077428] Funding Source: NIH RePORTER
- NHLBI NIH HHS [R01 HL080137-02, R01 HL063414-03, R01 HL080137, R01 HL063414-05A1, R01 HL063414, R01 HL077428-01A2, R01 HL063414-01, R01 HL057516, R01 HL057516-08, R01 HL077428-02, R01 HL063414-08, R01 HL057516-07, R01 HL057516-09, R01 HL077428, R01 HL057516-06, R01 HL057516-11, R01 HL057516-05, R01 HL063414-07, R01 HL057516-10, R01 HL063414-06, R01 HL080137-01A1, R01 HL063414-04, R01 HL063414-02] Funding Source: Medline
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Armed with an improved understanding of the mediators of angiogenesis, physicians and scientists have made significant efforts at harnessing this naturally occurring process in order to treat patients with a variety of peripheral vascular and coronary ischemic syndromes. There is a growing population of patients with end-stage coronary artery disease (CAD) who are no longer candidates for mechanical revascularization, yet suffer from chronic myocardial ischemia who may benefit from regeneration of the depleted microvasculature. (C) 2007 Elsevier Inc. All rights reserved.
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