Journal
DISEASE MARKERS
Volume 23, Issue 5-6, Pages 453-457Publisher
HINDAWI LTD
DOI: 10.1155/2007/674058
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Funding
- NATIONAL INSTITUTE ON AGING [Z01AG000397, ZIAAG000397, Z01AG000512] Funding Source: NIH RePORTER
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Members of the claudin family of tight junction proteins have been found altered in several malignancies, including ovarian cancer. Because claudin-3 and -4 are elevated in the vast majority of ovarian tumors, they may represent useful biomarkers for detection and prognosis, as well as ideal targets for therapy using the Clostridium perfringens enterotoxin.
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