Journal
CANCER EPIDEMIOLOGY
Volume 37, Issue 1, Pages 60-63Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.canep.2012.07.007
Keywords
CSCs; Metastasis; EMT; MicroRNAs; Angiogenesis
Funding
- China Postdoctoral Science Foundation [20100480542, 201104227]
- Nature Science Foundation of Shanghai [12ZR1436000]
- Youth Innovation Promotion Association, Chinese Academy of Sciences
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Recent studies have identified the important role of cancer stem cells (CSCs) in carcinogenesis and relapse. However, with respect to multistage cancer metastasis, the role of CSCs has not been well-defined. In several human cancers, data showed that some phenotypic subsets of CSCs were responsible for cancer metastasis. In this review, we surveyed recent advances in the role and mechanism of metastatic CSCs. (C) 2012 Elsevier Ltd. All rights reserved.
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