4.8 Editorial Material

Cancer-Specific Splicing Changes and the Potential for Splicing-Derived Neoantigens

Journal

CANCER CELL
Volume 34, Issue 2, Pages 181-183

Publisher

CELL PRESS
DOI: 10.1016/j.ccell.2018.07.008

Keywords

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Funding

  1. Pancreatic Cancer Action Network-AACR Pathway to Leadership Program
  2. National Pancreas Foundation
  3. NIH/NHLBI [R01 HL128239]
  4. Department of Defense Bone Marrow Failure Research Program [W81XWH-16-1-0059]
  5. Starr Foundation [I8-A8-075]
  6. Henry & Marilyn Taub Foundation
  7. Edward P. Evans Foundation
  8. Leukemia and Lymphoma SocietyLeukemia and Lymphoma Society
  9. Pershing Square Sohn Cancer Research Alliance

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In this issue of Cancer Cell, Kahles et al. perform a comprehensive analysis of RNA splicing across cancer types and identify novel correlations between genetic alterations and splicing in cancer. In addition, they identify that tumor-specific splicing has the potential to generate a large new class of tumor-specific neoantigens.

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