Journal
CANCER CELL
Volume 23, Issue 6, Pages 713-715Publisher
CELL PRESS
DOI: 10.1016/j.ccr.2013.05.012
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There is much interest in defining the nutrient dependencies of cancer cells and their mechanisms of adaptation to nutrient depletion. In a recent issue of Cell, Leprivier and colleagues demonstrate that eEF2K, which can inhibit translation elongation acutely during protein synthesis, is a critical switch in the survival versus death fate of starved cancer cells.
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