Journal
CANCER CELL
Volume 23, Issue 3, Pages 265-267Publisher
CELL PRESS
DOI: 10.1016/j.ccr.2013.02.021
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Cancer stem cells display an epithelial-mesenchymal transition phenotype and are resistant to current therapies. In this issue of Cancer Cell, Dong and colleagues demonstrate that these phenotypes in basal-like breast cancer are promoted by a metabolic switch to glucose metabolism, resulting in decreased reactive oxygen species levels.
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