4.8 Editorial Material

ABT-199: Taking Dead Aim at BCL-2

Journal

CANCER CELL
Volume 23, Issue 2, Pages 139-141

Publisher

CELL PRESS
DOI: 10.1016/j.ccr.2013.01.018

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Funding

  1. NCI NIH HHS [T32 CA009172, R01 CA129974] Funding Source: Medline

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ABT-199 is a new selective small molecule inhibitor of BCL-2 that appears to spare platelets while achieving potent antitumor activity. Assays that can predict the efficacy of ABT-199 in individual tumors will be critical in determining how best to incorporate this promising agent into the armamentarium of cancer therapies.

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