Journal
CANCER CELL
Volume 22, Issue 6, Pages 701-703Publisher
CELL PRESS
DOI: 10.1016/j.ccr.2012.11.015
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Funding
- NCI NIH HHS [P01 CA134292] Funding Source: Medline
- NIDDK NIH HHS [P30 DK079637] Funding Source: Medline
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In this issue of Cancer Cell, Kopp and colleagues report that pancreatic ductal cells are largely refractory to the induction of pancreatic neoplasia. Whereas a rare ductal subpopulation may still prove capable of neoplastic transformation, these findings refocus attention on acinar and other non-ductal cell types as initiators of this deadly neoplasm.
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