4.8 Editorial Material

Breaking the LSD1/KDM1A Addiction: Therapeutic Targeting of the Epigenetic Modifier in AML

Journal

CANCER CELL
Volume 21, Issue 4, Pages 451-453

Publisher

CELL PRESS
DOI: 10.1016/j.ccr.2012.03.027

Keywords

-

Funding

  1. NCI NIH HHS [R01 CA155328] Funding Source: Medline
  2. NHLBI NIH HHS [R01 HL087188] Funding Source: Medline

Ask authors/readers for more resources

KDM1A/LSD1, a histone H3K4/K9 demethylase and epigenetic regulator with roles in both gene activation and repression, has increased expression in multiple cancer types. Harris et al., in this issue of Cancer Cell, and Schenk et al. show that KDM1A may be a viable therapeutic target in treating AML.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.8
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

No Data Available
No Data Available