4.8 Editorial Material

Resisting Targeted Therapy: Fifty Ways to Leave Your EGFR

Journal

CANCER CELL
Volume 19, Issue 4, Pages 437-440

Publisher

CELL PRESS
DOI: 10.1016/j.ccr.2011.03.020

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Funding

  1. Cancer Research UK [11566] Funding Source: Medline
  2. Cancer Research UK [11566] Funding Source: researchfish

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Despite the promise of the new generation of molecularly targeted drugs, intrinsic and acquired resistance is proving to be as problematic as with cytotoxic drugs. Two recent papers have identified novel ways by which non-small cell lung cancers can exhibit resistance to EGFR inhibitors and suggest new therapeutic workarounds.

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