Journal
VIRTUAL AND PHYSICAL PROTOTYPING
Volume 2, Issue 4, Pages 217-223Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/17452750701747278
Keywords
Tissue engineering; Solid freeform fabrication; Biomaterials; Electrowetting; Hydrogel scaffold
Funding
- National Science Foundation (NSF) [0700139]
- Machine Shop of Drexel University
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To overcome limitations of current tissue fabrication methods, explore new biocompatible materials, and develop new biomimetic manufacturing process for soft tissue, we are developing a new technology, electrowetting-based microfluidics array printing, which will be used in a solid freeform fabrication (SFF) system to meet the challenges of high resolution manufacture of hydrogel scaffolds with dimension scale less than 10 mm, cell placement, growth factor delivery, and vascularization for soft tissue engineering. Preliminary work has been done on the biomaterials research, electrowetting printing, biomimetic modeling, scaffold fabrication, and system integration and control. This research is the first application of electrowetting on dielectric to tissue engineering and dispensing hydrogels.
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