Journal
CANCER CAUSES & CONTROL
Volume 22, Issue 2, Pages 311-318Publisher
SPRINGER
DOI: 10.1007/s10552-010-9691-6
Keywords
Epidemiology; Risk factors; Prostate cancer
Funding
- Department of Health and Social Security
- Tobacco Research Council
- British Heart Foundation
- Academy of Finland, Finland
- National Heart, Lung, and Blood Institute [R01HL036310-20A2]
- National Institute on Aging [R01AG034454-01]
- NIH, US
- MRC
- Chief Scientist Office at the Scottish Government Health Directorates
- MRC [MC_U137686857, G0902037, G0600705] Funding Source: UKRI
- British Heart Foundation [RG/07/008/23674] Funding Source: researchfish
- Medical Research Council [MC_U137686857, G8802774, G0100222, G0600705, G19/35, G0902037] Funding Source: researchfish
Ask authors/readers for more resources
The determinants of prostate cancer--aside from established but non-modifiable risk factors of increased age, black ethnicity, and a positive family history--are poorly understood. We examined the association of a series of baseline socioeconomic, behavioral, and metabolic characteristics with the risk of prostate cancer mortality in a 40-year follow-up of study members from the original Whitehall cohort study. During this period there were 578 prostate cancer deaths in 17,934 men. After adjustment for a series of baseline covariates, results from proportional hazards regression analyses indicated that marital status (hazard ratio; 95% confidence interval: widowed/divorced vs. married: 1.44; 0.95, 2.18), raised blood cholesterol (tertile 3 vs. 1: 1.35; 1.11, 1.65), and increased physical stature (tertile 3 vs. 1: 1.37; 1.09, 1.74) were associated with death from prostate cancer, although statistical significance at conventional levels was not apparent in all analyses. There was no evidence that physical activity, smoking habit, socio-economic status, component of either blood pressure or diabetes predicted the risk of death from this malignancy herein. In the present study, there was a suggestion that marital status, blood cholesterol, and height were risk indices for death from prostate cancer.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available