Journal
TETRAHEDRON LETTERS
Volume 48, Issue 1, Pages 141-143Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2006.10.142
Keywords
aza-Michael reaction; beta-amino carbonyl compound; amine; conjugated alkene; water
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The addition of amines to conjugated alkenes has been carried out in water at room temperature very efficiently without any catalyst. Significant rate acceleration of this reaction is observed in water compared to organic solvents. (c) 2006 Elsevier Ltd. All rights reserved.
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