Journal
JOURNAL OF BONE AND MINERAL RESEARCH
Volume 22, Issue 1, Pages 64-71Publisher
AMER SOC BONE & MINERAL RES
DOI: 10.1359/JBMR.061006
Keywords
spaceflight; bone formation; bone matrix proteins; histomorphometry; osteoblasts; mu CT
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Funding
- NIAAA NIH HHS [AA 011140] Funding Source: Medline
- NIAMS NIH HHS [AR 48833] Funding Source: Medline
- NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES [R01AR048833] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM [R01AA011140] Funding Source: NIH RePORTER
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HLU suppressed bone formation and resulted in bone loss in the tibial metaphysis of 6-month-old male rats. A human therapeutic dose of intermittent PTH (I mu g/kg/day) prevented the skeletal changes associated with HLU.
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