4.7 Article

Design, synthesis and biological evaluation of a macrocyclic discodermolide/dictyostatin hybrid

Journal

CHEMICAL COMMUNICATIONS
Volume -, Issue 1, Pages 49-51

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b615122a

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A 22-membered macrocyclic discodermolide/dictyostatin hybrid has been designed and synthesised; biological evaluation against a range of human cancer cell lines revealed significant levels of growth inhibition.

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