4.7 Article

Palladium-catalyzed conjugate reduction of enones into alpha,beta-dideuterioketones with hexamethyldisilane and deuterium oxide

Journal

CHEMICAL COMMUNICATIONS
Volume -, Issue 18, Pages 1819-1821

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b618107d

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Conjugated enones are reduced by readily available Me3SiSiMe3 and D2O in the presence of a catalytic amount of [PdCl(eta(3)-C3H5)](2) - PPh3 to give alpha,beta-dideuterioketones.

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