4.7 Article

Alkylation of active methylene compounds with alcohols catalyzed by an iridium complex

Journal

CHEMICAL COMMUNICATIONS
Volume -, Issue 27, Pages 2850-2852

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b702293j

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Base-free catalytic alpha-alkylation of active methylene compounds with primary alcohols was successfully achieved using an [IrCl(cod)] complex in the presence of PPh3 to afford the corresponding saturated alpha-alkylated products in good yields.

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