4.7 Article

An alkoxide-directed alkyne-allene cross-coupling for stereoselective synthesis of 1,4-dienes

Journal

CHEMICAL COMMUNICATIONS
Volume -, Issue 43, Pages 4531-4533

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b708256h

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Funding

  1. NIGMS NIH HHS [GM80266, R01 GM080266] Funding Source: Medline
  2. NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R01GM080266] Funding Source: NIH RePORTER

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A titanium alkoxide-mediated convergent coupling between internal alkynes and allenes is described for the regio- and stereocontrolled synthesis of substituted acyclic 1,4-dienes.

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