4.5 Letter

In vitro antiviral effect of meroditerpenes isolated from the Brazilian seaweed Stypopodium zonale (Dictyotales)

Journal

PLANTA MEDICA
Volume 73, Issue 11, Pages 1221-1224

Publisher

GEORG THIEME VERLAG KG
DOI: 10.1055/s-2007-981589

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The meroditerpenoids atomaric acid (1), epitaondiol (2) and the peroxylactone of 5'a-desmethyl-5'-acetylatomaric acid (3) were isolated from the Brazilian brown alga Stypopodium zonale collected in two localities (Buzios and Marataizes, RJ and ES States). These compounds showed strong anti-HSV-1 activity in vitro but neither of them inhibited the transcriptase reverse enzyme of HIV-1.

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