Journal
DALTON TRANSACTIONS
Volume -, Issue 15, Pages 1500-1508Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/b613629j
Keywords
-
Categories
Ask authors/readers for more resources
The pharmacologically active [Ru(CO)(3)Cl(glycinate)] is shown to be in equilibrium with [Ru(CO)(2)(CO2H) Cl(glycinate)](-) (isomers) at around pH 3.1 which then at physiological pH reacts with more base to give [Ru(CO)(2)(CO2) Cl(glycinate)](2-) (isomers) or [Ru(CO)(2)(CO2H)(OH)(glycinate)](-)( isomers). The ease with which [Ru(CO)(3)Cl( glycinate)] reacts with hydroxide results in it producing a solution in water with a pH of around 2 to 2.5 depending on concentration and making its solutions more acidic than those of acetic acid at comparable concentrations. Acidification of [Ru(CO)(3)Cl(glycinate)] with HCl gives [Ru(CO)(3)Cl-2(NH2CH2CO2H)]. The crystal structures of [Ru(CO)(3)Cl(glycinate)] and [Ru(CO)(3)Cl-2(NH2CH2CO2Me)] are reported.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available