Journal
JOURNAL OF CLINICAL MICROBIOLOGY
Volume 45, Issue 1, Pages 237-240Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/JCM.01429-06
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Funding
- Wellcome Trust [072402/Z/03/Z] Funding Source: Medline
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Evolution of the direct repeat region in Mycobacterium tuberculosis has created unique spoligotype signatures specifically associated with IS6110-defined strain families. Spoligotyping signatures may enable the analysis of the strain population structure in different settings and will enable the rapid identification of strain families that acquire drug resistance or escape protective immunity in drug and vaccine trials.
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