4.8 Article

Semiconductor quantum rods as single molecule fluorescent biological labels

Journal

NANO LETTERS
Volume 7, Issue 1, Pages 179-182

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/nl0626434

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Funding

  1. NCRR NIH HHS [P41 RR019664] Funding Source: Medline
  2. NIGMS NIH HHS [R01 GM070445, GM070445] Funding Source: Medline
  3. PHS HHS [0980GFD623] Funding Source: Medline
  4. NATIONAL CENTER FOR RESEARCH RESOURCES [P41RR019664] Funding Source: NIH RePORTER
  5. NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R01GM070445] Funding Source: NIH RePORTER

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In this paper, we report the development of rod-shaped semiconductor nanocrystals (quantum rods) as fluorescent biological labels. Water-soluble biocompatible quantum rods have been prepared by surface silanization and applied for nonspecific cell tracking as well as specific cellular targeting. Quantum rods are brighter single molecule probes as compared to quantum dots. They have many potential applications as biological labels in situations where their properties offer advantages over quantum dots.

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